INNOVATIONS IN REGENERATIVE MEDICINE

Stem Cells Culture Media

As the youngest stem cells in the connective tissue lineage, mesenchymal stem cells (MSCs) support the development of skin, hair, bone, muscle, and cartilage. More than any other exosomes, those produced by neonatal MSCs display significant regenerative potential, suppressing inflammation, reducing oxidative stress, advancing cell survival, and healing injured tissue.

Recognizing their exceptional therapeutic benefits, Kimera Society supports research that forwards clinical applications of MSC exosomes. Isolated MSC cultures are necessary to conduct that research, a process optimized by Kimera Labs. To ensure the purity of these exosomes after isolated MSCs are cultured, the methodology involves:

  1. Sterile-filtering the conditioned media and the exosomes to remove the cells
  2. Subjecting the exosomes to serial purification that removes constituents of the conditioned media, yielding isolated MSC exosomes
  3. Testing each lot of the MSC exosomes for viral, bacterial, and endotoxin contamination
  4. Confirming isolated MSC exosomes through such modalities as protein and RNA sequencing, Nano Tracking Analysis, and STORM super resolution fluorescence microscopy